[Sign Up Now] to Receive Our FREE Daily SCVTV-SCVNews Digest by E-Mail

Inside
Weather
Santa Clarita CA
Mostly clear
Mostly clear
85°F
 
Calendar
Today in
S.C.V. History
August 16
1956 - Battle of Palmdale rages over the skies of Santa Clarita [story]


Two cardiology investigators from the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at UCLA have been awarded grants totaling more than $6 million from the California Institute of Regenerative Medicine (CIRM), the state’s stem cell agency.

The young physician–scientists, Dr. Reza Ardehali and Dr. Ali Nsair, will use the CIRM funds to conduct leading-edge research into the developmental and molecular biology of stem cells in their efforts to advance regenerative medicine for heart disease. Their studies will help form the foundation for translational and clinical advances, enabling human stem cells to be used for potential therapies and as tools for biomedical innovation.

The CIRM grants, known as New Faculty Physician Scientist Translational Research Awards, are given to clinician–scientists in the first six years of their first independent faculty appointments. The awards were announced Dec. 12 during the regular meeting of the CIRM Independent Citizens Oversight Committee at the Luxe Hotel in Los Angeles.

Dr. Reza Ardehali

Dr. Reza Ardehali

Dr. Reza Ardehali

Dr. Reza Ardehali, an assistant professor of cardiology and a member of the Broad Stem Cell Research Center, was awarded more than $2.9 million for research to isolate heart stem cells derived from human embryonic stem cells — cells that can  become any cell in the body — to determine if these heart cells can be integrated successfully into the environment of a living heart or if they will function in isolation at a different pace.

Ardehali uses an analogy: “The performance of a symphony can go into chaos if one member plays in isolation from all surrounding cues. Therefore, it is important to determine if the transplanted cells can beat in harmony with the rest of the heart and if these cells will provide functional benefit to the injured heart.”

Ardehali will transplant the heart stem cells into injured hearts in an animal model to determine if the cells improve heart function. He also will perform detailed analysis of the electrical activities of the heart to determine how well the stem cells grow and integrate into new heart tissue. The success of this proposed project could lead to future clinical trials of stem cell therapy for heart disease.

Dr. Ali Nsair

Dr. Ali Nsair

Dr. Ali Nsair

Dr. Ali Nsair, an assistant professor of medicine and cardiology and a member of the Broad Stem Cell Research Center, was awarded more than $3 million for research using induced pluripotent stem cells — tissue-specific blood or skin cells that have been reprogrammed to become like human embryonic stem cells — to develop heart tissue cells known as cardiac progenitor cells. Once these cardiac progenitor cells are grown in the laboratory, they will be used to regenerate heart muscle damaged by heart attack.

The Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research: UCLA’s stem cell center was launched in 2005 with a UCLA commitment of $20 million over five years. A $20 million gift from the Eli and Edythe Broad Foundation in 2007 resulted in the renaming of the center. With more than 200 members, the Broad Stem Cell Research Center is committed to a multidisciplinary, integrated collaboration among scientific, academic and medical disciplines for the purpose of understanding adult and human embryonic stem cells. The center supports innovation, excellence and the highest ethical standards focused on stem cell research with the intent of facilitating basic scientific inquiry directed toward future clinical applications to treat disease. The center is a collaboration of the David Geffen School of Medicine at UCLA, UCLA’s Jonsson Cancer Center, the UCLA Henry Samueli School of Engineering and Applied Science and the UCLA College of Letters and Science.

Comment On This Story
COMMENT POLICY: We welcome comments from individuals and businesses. All comments are moderated. Comments are subject to rejection if they are vulgar, combative, or in poor taste.
REAL NAMES ONLY: All posters must use their real individual or business name. This applies equally to Twitter account holders who use a nickname.

0 Comments

You can be the first one to leave a comment.

Leave a Comment


HIGHER EDUCATION LINKS
LOCAL COLLEGE HEADLINES
Thursday, Aug 16, 2018
College of the Canyons is partnering with AMS Fulfillment to offer 30 pre-apprenticeships in the logistics field—one of the fastest growing industries in Los Angeles County—to individuals who need job readiness skills to gain employment.
Tuesday, Aug 14, 2018
Your personal brand is the engine of a successful career. Having a strong online presence can lead to new jobs and career opportunities.
Thursday, Aug 9, 2018
It’s not too late to apply for a year of free tuition through the College of the Canyons First-Year Promise Plus program. College of the Canyons has extended the application deadline until the 500-student limit is reached.
Wednesday, Aug 8, 2018
C.L. Max Nikias was formally removed as president of the University of California and engineer-businesswoman Dr. Wanda M. Austin named Interim President on Tuesday, according to USC Board of Trustees Chairman Rick J. Caruso.
Wednesday, Aug 8, 2018
The Santa Clarita Community College District’s Board of Trustees meeting, scheduled for Wednesday, Aug. 8, has been canceled and rescheduled.
Keep Up With Our Facebook

Latest Additions to SCVNews.com
The County of Los Angeles Department of Parks and Recreation, in collaboration with The Friends of Hart Park, presents its, “7th Annual Summer Movies in the Park Series."
Aug. 17: Black Panther to Close Out Summer Movies in the Park Series
LANCASTER – The University of Antelope Valley (UAV) baseball program is pleased to announce the additions of 6-1 utility player Edmond Marcotte, 6-0 utility player Kyle Lathrop, and 6-1 pitcher Austin Grabbit, with all three players coming over to UAV from Antelope Valley College in Lancaster, Calif.
University of Antelope Valley Adds 3 New Players to Baseball Program
College of the Canyons is partnering with AMS Fulfillment to offer 30 pre-apprenticeships in the logistics field—one of the fastest growing industries in Los Angeles County—to individuals who need job readiness skills to gain employment.
COC Partners with Local Fulfillment Company to Offer Pre-Apprenticeships
Children and young adults need to be protected before heading back to school.
County Encourages Parents to Stay Current on School Immunizations
Well, I don't know but I've been told, you’ll never slow down, you’ll never grow old with the music of Tom Petty and the Heartbreakers.
Tom Petty & the Heartbreakers Tribute Band Free Falls into Concerts in the Park
Mayor Laurene Weste, Mayor Pro Tem Marsha McLean, Councilmembers Bob Kellar, Bill Miranda and Cameron Smyth cordially invite you to the 2018 State of the City Luncheon to be held on Thursday, Oct. 25, at 11:30 a.m., at the Hyatt Regency Valencia.
Oct. 25: “Santa Clarita – City of the Arts” State of the City Luncheon
To keep grass at parks green and lush despite constant use, the city of Santa Clarita Parks division works hard to maintain the high quality fields residents love.
City Aerates, Renovates Parks Ahead of Fall
The Saugus Union School District is very pleased to announce the awarding of two grants to provide arts education in the district.
County Arts Commission, Music Center Awarding Grants to Saugus Union
The New Heights Artist Development Series will be holding a free presentation on taxes and artists.
Aug. 23: New Heights Artist Development Series, “Taxes and the Artist”
After thirteen years of service, Saugus Union School District (SUSD) Governing Board Member Paul De La Cerda announced on Friday that he will not be seeking re-election.
Saugus School Board Member to Pursue Doctorate; Won’t Seek Re-Election
LANCASTER, Calif. – On the heels of their longest winning streak of the season, the Lancaster JetHawks are in the midst of their longest losing streak after a 6-4 defeat at the hands of Stockton Wednesday night at The Hangar. The loss was Lancaster’s fifth in a row.
Stockton Hands JetHawks 5th Straight Loss
Los Angeles County Sheriff’s Department’s Missing Persons Unit detectives are seeking the public’s assistance in locating Wayne Stuart Habell.
Detectives Seek Help in Locating Missing Fire Captain
LOS ANGELES – According to the South Coast Air Quality Management District, air quality will be unhealthy for sensitive individuals in Santa Clarita Valley tomorrow, Friday, Aug. 17.
Unhealthy Air Quality Declared in SCV Friday
1956 - Battle of Palmdale rages over the skies of Santa Clarita [story]
The Los Angeles County Board of Supervisors has selected Ricardo Garcia to be the county’s new Public Defender.
Supes Name Ricardo Garcia New LA County Public Defender
The seven Los Angeles County animal shelters including the Castaic Animal Care Center will offer $20 adoption fees for dogs and free adoption for cats on Saturday, August 18 from 10 a.m. to 6 p.m.
Aug. 18: Cheap, Free Pet Adoptions at Castaic Shelter
The U.S. Interior Department is against adding the Rim of the Valley Corridor to the Santa Monica Mountains National Recreation area, and it won't take a stand on the proposed St. Francis Dam Memorial legislation because it's an issue for the Agriculture Department, not the Interior Department.
Park Service Opposes Rim Addition, Defers on Dam Bill
Air quality will be unhealthy for sensitive people in the SCV on Thursday, according to an advisory from the South Coast Air Quality Management District.
Air Quality Unhealthy for SCV Residents Thursday
FOX Sports Prime Ticket, in partnership with the CIF Southern Section, will launch its TV-web coverage of the 2018 high school football season on Friday, Aug. 17.
Aug. 17: Friday Night High School Football Returns to Prime Ticket
The Lancaster JetHawks scored twice and put the tying run on base in the bottom of the ninth inning, but it was not enough in a 5-4 loss to the Stockton Ports Tuesday night at The Hangar.
Late JetHawks Rally Comes Up Short Against Ports
The Los Angeles Dodgers reinstated left-handed pitcher Alex Wood from the 10-day disabled list Thursday and placed right-handed pitcher John Axford on the 10-day disabled list with a fractured right fibula.
Dodgers Reinstate Pitcher Alex Wood
The Santa Clarita Valley Sheriff's Station has released its crime and public safety information report for Stevenson Ranch (Zone 3) for the week of Aug. 6-12, 2018.
Crime Blotter: Grand Theft, GTA in Stevenson Ranch
1849 - Eight-pound gold nugget found in San Feliciano Canyon (Val Verde/Piru area) [story]
Here is a list of Santa Clarita arts-related events for Aug. 15 - Aug. 17:
Aug. 15-17: Santa Clarita Arts Calendar
Walk season is quickly approaching, and it's time to turn up the heat in the fight to end Alzheimer's.
Walk to End Alzheimer’s Offers up New Challenge
Twelve people are challenging incumbent Mayor Laurene Weste, Mayor Pro-tem Marsha McLean and Councilman Bill Miranda in the upcoming November 6 election. They are:
List of Candidates Running for City Council Released
As always with the schools, there is going to be congestion twice per day with the drop off and pick up of students. Drivers need to be extra patient in these areas to help traffic flow.
SCV Sheriff’s Offer Back to School Safety Tips
The Valley Industry Association will be holding its, "Hot August Nights Party," on Thursday, Aug. 23, from 5:30 p.m. to 7:30 p.m. for a night of fun, friends and a little business.
Aug. 23: Valley Industry Association’s Hot August Nights Party
Your personal brand is the engine of a successful career. Having a strong online presence can lead to new jobs and career opportunities.
COC’s Community Education to Hold Personal Branding Workshop
The Canyon Country Advisory Committee (CCAC) will hold their next meeting Wednesday, Aug. 15 from 7:00 p.m. - 9:00 p.m.
Aug. 15: Canyon Country Advisory Committee Meeting
Santa Clarita RE/MAX Realtor Josh Sinatra, of Sinatra Real Estate, spearheads back-to-school donation drive to help people in need.
Local Realtor Hosting Shoe Donation Drive for People in Need
Henry Mayo Newhall Hospital is pleased to announce that Logix Federal Credit Union has generously stepped forward to sponsor a palliative care teddy bear program at the hospital to help children feel supported and comforted when faced with the passing of a parent.
Logix Steps Forward to Help Henry Mayo’s Palliative Bear Program
The Santa Clarita Valley Special Education Local Plan Area (SELPA) actively encourages parents or community members who know of a child (birth to age 22) who may have special needs to contact their local school district office.
SCV School Districts Providing Services for Students with Special Needs
The WiSH Education Foundation is thrilled to announce that its fourth annual signature event, Cocktails on the Roof, is back on Sept. 7, 2018. The event runs from 8:00 p.m. - 11:00 p.m.
Sept. 7:  Cocktails on the Roof Benefiting WiSH Foundation
Here is the Newhall Public Safety and Crime Information Report for July 30, 2018 - Aug. 5, 2018:
Crime Blotter: Petty Theft, Commercial Burglary in Newhall
RANCHO CUCAMONGA – After sweeping Rancho Cucamonga in Lancaster last weekend, the JetHawks were swept by the Quakes at LoanMart Field after falling Sunday afternoon, 5-2. The JetHawks scored the first two runs of the game, but were held to just three hits after.
Quakes Sweep JetHawks