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Today in
S.C.V. History
March 23
1886 - Film director Robert N. Bradbury born in Washington state; launched John Wayne's career in Placerita Canyon [watch]

Product Safety Bar

Oxyelite ProUSPlabs LLC recalls OxyElite Pro dietary supplements; products linked to liver illnesses
FDA announced  that USPlabs LLC, of Dallas, Texas, is recalling certain OxyElite Pro dietary supplement products that the company markets. The company took this action after receiving a letter from the FDA stating that the products have been linked to liver illnesses and that there is a reasonable probability that the products are adulterated. The letter also notified USPlabs that if the company did not initiate a voluntary recall, the FDA could by law order the company to immediately stop distributing the dietary supplements and immediately notify other parties to stop distributing the dietary supplements.
More information
iclusigFDA asks manufacturer of the leukemia drug Iclusig (ponatinib) to suspend marketing and sales
FDA is providing instructions to health care professionals whose patients have been taking Iclusig (ponatinib) and are benefiting from the drug, on how to continue those patients on the drug. We are working closely with Iclusig’s manufacturer, ARIAD Pharmaceuticals (ARIAD), to avoid interruptions in treatment.  At this time, Iclusig treatment may be continued for appropriate patients under an emergency Investigational New Drug (IND) application. More information. This information is a follow up to the FDA Drug Safety Communication: FDA asks manufacturer of the leukemia drug Iclusig (ponatinib) to suspend marketing and sales issued on October 31, 2013
drug shortagesFDA takes two important actions on drug shortages
FDA is taking two actions to further enhance the agency’s ongoing efforts to prevent and resolve drug shortages, a significant public health threat that can delay, and in some cases even deny, critical care for patients. Following the President’s 2011 Executive Order on reducing drug shortages, the number of new shortages in 2012 was 117, down from 251 in 2011.  The announcements build on this work. First, the FDA is releasing a strategic plan called for in the Food and Drug Administration Safety and Innovation Act (FDASIA) of 2012 to improve the agency’s response to imminent or existing shortages, and for longer term approaches for addressing the underlying causes of drug shortages. The plan also highlights opportunities for drug manufacturers and others to prevent drug shortages by promoting and sustaining quality manufacturing. More information 
fingerComunicaciones de la FDA sobre la seguridad de los medicamentos en español
Descargo de responsabilidad: La FDA reconoce la necesidad de proporcionar información sobre seguridad importante en idiomas distintos al inglés. Hacemos lo mejor posible  para proporcionar  versiones en español precisas y oportunas de nuestras Comunicaciones de Seguridad de Medicamentos. Sin embargo, en caso que existiera discrepancias entre las versiones en ingles y en español, la información contenida en la versión en inglés es la que se considera como versión oficial. Si tiene alguna pregunta, por favor contáctese con Division of Drug Information en druginfo@fda.hhs.gov. Comunicaciones de la FDA
MedWatch Logo
MedWatch: The FDA Safety Information and Adverse Event Reporting Program
For more important safety information on human drug and devices or to report a serious problem, please visit MedWatch.

Product Short and DC

Drug ShortageFDA recognizes the significant public health consequences that can result from drug shortages and takes tremendous efforts within its legal authority to address and prevent drug shortages. These shortages occur for many reasons, including manufacturing and quality problems, delays, and discontinuations. When issues are discovered by the company or the public and reported to FDA or are found by FDA upon inspection, FDA works closely with the firm to address risks involved to prevent harm to patients. FDA also considers the impact a shortage would have on patient care and access and works with the firm to restore supplies while also ensuring safety for patients. More information 

Drug Shortages Voluntarily Reported by Manufacturers During the Past 2 Weeks:


  • Tiopronin (Thiola)


Drug Shortages Resolved During the Past 2 Weeks:


  • Dexrazoxane Injection
  • Fluticasone Propionate and Salmetrerol (Advair HFA)










Product Approval Bar

FDA ApprovedGazyva for chronic lymphocytic leukemia approved
FDA approved Gazyva (obinutuzumab) for use in combination with chlorambucil to treat patients with previously untreated chronic lymphocytic leukemia (CLL). Gazyva works by helping certain cells in the immune system attack cancer cells. Gazyva is intended to be used with chlorambucil, another drug used to treat patients with CLL.
Gazyva is the first drug with breakthrough therapy designation to receive FDA approval.
More information

Aptiom approved to treat seizures in adults
FDA approved Aptiom (eslicarbazepine acetate) as an add-on medication to treat seizures associated with epilepsy. Epilepsy is a brain disorder caused by abnormal or excessive activity in the brain’s nerve cells. Approximately 200,000 new cases of seizures and epilepsy occur in the United States each year. Aptiom is approved for the treatment of partial seizures, the most common type of seizure seen in people with epilepsy. Seizures can cause a wide range of symptoms, including repetitive limb movements, unusual behavior and generalized convulsions with loss of consciousness. Seizures can have serious consequences, including injury and death.
More information

Drugs@FDAFor information on drug approvals or to view prescribing information and patient information, please visit Drugs@FDA or DailyMed.

Comments and Guidances

Unique Device Identification System
FDA is issuing a final rule to establish a system to adequately identify devices through distribution and use. This rule requires the label of medical devices to include a unique device identifier (UDI), except where the rule provides for an exception or alternative placement. The labeler must submit product information concerning devices to FDA’s Global Unique Device Identification Database (GUDID), unless subject to an exception or alternative. More information

View current opportunities for comment on topics of interest for patients and caregivers.

Announcements Bar

E. ColiFDA Investigates Multistate Outbreak of E. coli O157 Illnesses Possibly Linked to Pre-packaged Salad Products 

janssen pharmaceuticalJanssen Pharmaceuticals, Inc. to plead guilty and pay over $1.6 billion to resolve allegations of misbranding and filing false claims for its schizophrenia drug Risperdal
On behalf of the U.S. Food and Drug Administration, the U.S. Department of Justice today announced a guilty plea agreement with Janssen Pharmaceuticals, Inc., (JPI) of Titusville, N.J., and a $400 million criminal fine for introducing a misbranded drug, Risperdal (risperidone), into interstate commerce. A Johnson & Johnson Company, JPI must also pay $1.25 billion under a separate civil settlement concerning the same drug. The combined criminal plea and civil settlement agreement related to Risperdal totals more than $1.67 billion. More information 
Janet Woodcock June 2013Working to improve the communication of important drug safety information about generic drugs, by: Janet Woodcock, M.D., Director of Center for Drug Evaluation and Research
FDA is taking a step today that is intended to improve the communication of important drug safety information about generic drugs to both prescribers and patients.All drug manufacturers are required to keep close tabs on their drugs once they go to market, reviewing all reports of adverse events involving their drug and reporting these findings to FDA.

But currently, only brand name manufacturers are able to independently update and promptly distribute revised drug safety information, also called labeling, and they can distribute that information before FDA has reviewed or approved the change. These updates, which are submitted in changes being effected supplements, ensure that this important safety information gets to the public as quickly as possible.

To read the rest of this blog, see FDA Voice Blog, November 8, 2013


Dr. Hamburg - Official photoPersonalized Medicine: The Future is Now, by Margaret A. Hamburg, M.D., Commissioner of FDA
The difference between science and science fiction is a line that seems ever harder to distinguish, thanks in part to a host of astonishing advances in medical science that are helping to create a new age of promise and possibility for patients. 

Today cancer drugs are increasingly twinned with a diagnostic device that can determine whether a patient will respond to the drug based on their tumor’s genetic characteristics; medical imaging can be used to identify the best implantable device to treat a specific patient with clogged coronary arteries; and progress in regenerative medicine and stem cell therapy using a patient’s own cells could lead to the replacement or regeneration of their missing or damaged tissues. Given these trends, the future of medicine is rapidly approaching the promising level of care and cure once imagined by Hollywood in futuristic dramas like Star Trek.

To read the rest of this blog, see FDA Voice Blog, November 1, 2013

personalized medicinePersonalized Medicine :FDA’s Unique Role and Responsibilities in Personalized Medicine
The term “personalized medicine” is often described as providing “the right patient with the right drug at the right dose at the right time.”   More broadly, “personalized medicine” may be thought of as the tailoring of medical treatment to the individual characteristics, needs, and preferences of a patient during all stages of care, including prevention, diagnosis, treatment, and follow-up.Consistent with FDA’s core mission, the agency is working in collaboration with researchers, manufacturers of drugs, medical devices and biologics, health care professionals and others to better understand and adapt to the promise of personalized medicine.  FDA’s ongoing efforts to make personalized medicine possible touch on various facets of product development and use including:

Ucoming Meetings Bar

Advisory Committee Meeting at FDAFDA advisory committee meetings are free and open to the public. No prior registration is required to attend. Interested persons may present data, information, or views, orally at the meeting, or in writing, on issues pending before the committee.

Other types of meetings listed may require prior registration and fees.

View a complete list of upcoming public meetings and workshops.



fingerPlease visit FDA’s Advisory Committee page to obtain advisory committee meeting agendas, briefing materials, and meeting rosters prior to the meetings. You may also visit this page after meetings to obtain transcripts, presentations, and voting results. For additional information on other agency meetings please visit Meetings, Conferences, & Workshops.

Consumer Update bar

Types of transfatFDA Targets Trans Fat in Processed Foods
More than decade ago, a sea change began in the American diet, with consumers starting to avoid foods with trans fat and companies responding byreducing the amount of trans fat in their products.This evolution began when FDA first proposed in 1999 that manufacturers be required to declare the amount of trans fat on Nutrition Facts labels because of public health concerns. That requirement became effective in 2006. More information or to read press announcement.
teen lifitingTeens and Steroids: A Dangerous Combo
The abuse of anabolic steroids can cause both temporary and permanent injury to anyone using them. Teenagers, whose bodies are still developing, are at heightened risk. An alarming number of them are trying steroids in hopes of improving their athletic prowess or their appearance. Ali Mohamadi, M.D., a medical officer in the Food and Drug Administration’s Division of Metabolism and Endocrinology Products, warns teens and parents about the dangers of steroid use. More information
hearing lossHearing Loss Signals Need for Diagnosis
Straining to hear? Do people say you’re talking loudly? Thinking about ordering a hearing aid or sound amplifier from a magazine or late-night TV advertiser? 

Doing so could delay the diagnosis of a treatable or serious ear condition and lead to further hearing loss or other complications. “The problem might be as simple as a wax impaction blocking the ear canal, which is easily treated, or at the other end of the spectrum, it could be something as serious as a tumor pressing on the hearing nerve,” says Eric Mann, M.D., Ph.D., clinical deputy director for the Division of Ophthalmic, and Ear, Nose, and Throat Devices at FDA.
More information

More Consumer Updates
For previously published Consumer Update articles that are timely and easy-to-read and cover all FDA activities and regulated products. More information

Artículos en Español
Estos artículos para los consumidores incluyen información sobre la Administración de Medicamentos y Alimentos (FDA, Food and Drug Administration) y consejos para llevar una vida saludable. Artículos en Español

Food Safety Bar

holiday food safety Many people don’t realize that food safety is the most important ingredient in preparing food for the holidays. Below are some helpful food safety resources to keep your holidays happy:
Holiday Food Safety Success Kit
Holiday Food Safety Video
Ready-to-Cook Foods
Additional Information 
meeting for foodsGetting Importers’ Pulse About Food Safety Plans, from Michael R. Taylor, Deputy Commissioner for Foods and Veterinary Medicine
My team and I took to the road again recently to reach out to the people who will be most affected by the food safety rules that FDA has proposed this year. 

We traveled to Long Beach, Calif. – one of the world’s busiest ports – on Oct. 22 and 23 for a public meeting on the two rules that FDA proposed in July to help prevent contaminated foods from ever reaching U.S. ports. These rules – Foreign Supplier Verification Programs and Accreditation of Third-Party Auditors – would make importers more accountable for food safety and would strengthen our ability to monitor foreign food producers.

To read the rest of this blog, see FDA Voice Blog, November 4, 2013


Food SafetyCenter for Food Safety and Applied Nutrition
The Center for Food Safety and Applied Nutrition, known as CFSAN, carries out the mission of FDA. The Center provides services to consumers, domestic and foreign industry and other outside groups regarding field programs; agency administrative tasks; scientific analysis and support; and policy, planning and handling of critical issues related to food and cosmetics.
More information 

Food Facts for You
The Center for Food Safety and Applied Nutrition, known as CFSAN, issues food facts for consumers to keep you and your family safe. More information

Animal Health Bar

dog playing frisbeePain Medicines for Pets: Know the Risks
Your 9-year-old German Shepherd is limping, and you think that arthritis may be setting in. A trip to the veterinarian proves that you’re right—it’s osteoarthritis, a degeneration of the cartilage and bone that affects joints. The veterinarian prescribes a non-steroidal anti-inflammatory drug (NSAID).NSAIDs are a class of drugs extensively used in both human and veterinary medicine for their anti-fever, anti-inflammatory and pain-relieving properties, and they are the most commonly prescribed pain relievers for animals. Inflammation—the body’s response to irritation or injury—is characterized by redness, warmth, swelling, and pain. NSAIDs work by blocking the production of chemicals produced by the body that play a role in inflammation. More information
Dog with GlassesAnimal Health Literacy
Animal Health Literacy means timely information for the benefit of all animals and their humans. With continuous communication and outreach, the Center for Veterinary Medicine (CVM) strives to enhance the public trust, promote safe and effective use of the animal health products we regulate, and share our scientific endeavors. CVM provides reliable, science-based information to promote animal and human health. More information 


CVM Pet Facts
The Center for Veterinary Medicine (CVM) issues medical and feeding fact sheets to keep your pets healthy and safe. More information


Janet WoodcockHave a question about what the Center for Drug Evaluation and Research (CDER) does? Ask Janet Woodcock, M.D., Director, CDER, FDA
FDA will select some of your questions to answer each month. Due to the volume of e-mails we receive, we won’t be able to answer each question in this format. We may edit your questions for brevity or clarity.
More information 


To read questions and answers, see MailBag.

FDA On line ResourceFDA Basics
Each month, different centers and offices at FDA will host an online session where the public can ask questions to senior FDA officials about a specific topic or just listen in to learn more about FDA. More informationEducational Videos
FDA Food Safety and Modernization Act: An FDA Primer
The Rulemaking Process: An FDA Primer
What is Regulatory Science
Taking Acetaminophen Safely


Welcome to healthfinder.gov, a government Web site where you will find information and tools to help you and those you care about stay healthy. More information 

Tobacco Products Resources for You
Federal resources to help you quit using tobacco products and to help you learn more about youth tobacco prevention, effective treatment for nicotine addiction, and tobacco research and statistics.
More information






Take me to the web site

An interactive tool for educating patients, patient advocates, and consumers on how their medications – both prescription and over-the-counter ­– and medical devices move from the realm of idea to the realm of the marketplace. More information

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SCV NewsBreak
Friday, Mar 23, 2018
County Health Chief Extends Beach Use Advisory Through Sunday Night
Los Angeles County Interim Health Officer Dr. Jeffrey Gunzenhauser has extended a county beach use advisory through Sunday night at 11:30 due to runoff from the recent rainfall.
Friday, Mar 23, 2018
Knight, Feinstein Succeed in Killing CEMEX Mineral Rights in Soledad Canyon
The FY18 Omnibus Appropriations bill, signed into law by the president today, includes language that will ultimately conclude the decades-long dispute over the proposed CEMEX mineral mine in Soledad Canyon.
Friday, Mar 23, 2018
California High Court Rules Colleges Must Protect Students
The California Supreme Court ruled Thursday that colleges owe their students safety and protection from foreseeable violence in the classroom, reversing an appeals court’s finding that UCLA did not have a duty to protect a student who was attacked with a knife by a classmate in a chemistry lab.
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Latest Additions to SCVNews.com
The city of Santa Clarita’s Concerts in the Park series, presented by Logix Federal Credit Union, kicks off its 2018 season with Bon Jovi tribute band Wanted on Saturday, July 7 starting at 7 p.m.
July 7: Wanted Kicks Off 2018 Concerts in the Park Season
Los Angeles County Interim Health Officer Dr. Jeffrey Gunzenhauser has extended a county beach use advisory through Sunday night at 11:30 due to runoff from the recent rainfall.
County Health Chief Extends Beach Use Advisory Through Sunday Night
Jaiden France homered Friday for the third straight game, and Aaron Shackelford launched a three-run shot in the eighth inning to cement an 11-0 rout of Menlo College at Cartan Field in Atherton and continue his recent tear.
Mustang Baseball Takes Series Opener at Menlo 2-0
Nasmyth Group, a world leader and global supplier of precision engineering solutions in the aerospace industry based in the United Kingdom, held its grand opening of a new facility in the Santa Clarita Valley on Thursday.
Nasmyth TMF Celebrates Grand Opening in SCV
Santa Clarita Valley Economic Development Corporation chief Holly Schroeder outlines 10 really good reasons to live close to work.
SCVEDC’s Top 10 Benefits of Living Close to Work
The COC Center for Early Childhood Education and the Southern California Valley Association for the Education of Young Children will host the 15th annual "Play Day" on Saturday, April 14, from 10 a.m. to 2 p.m. in the COC Honor Grove on the college’s Valencia campus.
April 14: Play Day at COC Center for Early Childhood Education
CalArts alum Lauren Elizabeth Baba was profiled by Downbeat magazine in its March 2018 issue, in which she spoke of her time at CalArts, as well her latest album, 'Another Ride on the Elephant Slide.'
CalArts Alumna Lauren Elizabeth Baba Profiled in Downbeat Magazine
The FY18 Omnibus Appropriations bill, signed into law by the president today, includes language that will ultimately conclude the decades-long dispute over the proposed CEMEX mineral mine in Soledad Canyon.
Knight, Feinstein Succeed in Killing CEMEX Mineral Rights in Soledad Canyon
Cartoon Network premiered the animated buddy comedy "Apple & Onion" on "Adult Swim" on Feb. 23, featuring soundtrack score and theme song by CalArts alum Paul Fraser (Music MFA 11).
Cartoon Network’s ‘Apple & Onion’ Features Music by Paul Fraser
East of Borneo, a contemporary online art journal supported by CalArts School of Art, and LACMA present the fifth annual Art + Feminism meetup, a global do-it-yourself campaign to improve the coverage of women, feminism and the arts on Wikipedia at LACMA on Sunday, March 25, starting at noon.
March 25: Art + Feminism Wikipedia Edit-a-thon, Panel at LACMA
Master's sophomore Hannah Forrar has been named an NAIA Division 1 Women's Basketball All-American, the sixth straight year at least one Mustang has earned the honor.
TMU’s Forrar Keeps Streak of Women’s Basketball All-Americans Alive
Valencia-based Paseo Aquatics managed to finish in the top 15 out of 90 other clubs at the Southern California Swim 14 and Under Short Course Junior Olympic Championships last weekend.
Paseo Aquatics Finishes in Top 15 at Junior Olympics in Pasadena
Calvin Estrada and Josh Arkin both hit homers and starter Eddie Rosales tossed seven strong innings to help propel College of the Canyons to a 4-2 home conference victory over Barstow College at Cougar Field on Tuesday.
Canyons Picks Up 4-2 Win Over Barstow
The California Supreme Court ruled Thursday that colleges owe their students safety and protection from foreseeable violence in the classroom, reversing an appeals court’s finding that UCLA did not have a duty to protect a student who was attacked with a knife by a classmate in a chemistry lab.
California High Court Rules Colleges Must Protect Students
The next meeting of the Los Angeles County Board of Supervisors is set for Tuesday, March 27, starting at 1 p.m.
March 27: LA County Board of Supervisors Meeting
The SCV Senior Center has created the "2nd Career Center" to assist seniors who would like to re-enter the workforce, and the first "Job Club" meeting is set for Wednesday, March 28 from 10 a.m. to 11 a.m.
March 28: SCV Senior Center ‘2nd Career’ Job Club Meeting
The California Air Resources Board today adopted a regulation prohibiting the use of specific refrigerants known as hydrofluorocarbons, powerful chemicals that trap heat in the atmosphere at a rate thousands of times that of carbon dioxide.
California Acts to Limit Powerful Climate-Changing Chemicals
The SCV Man and Woman of the Year honor is awarded annually to individuals who have given many years of outstanding volunteer service to charitable organizations throughout the Santa Clarita Valley.
SCV Man, Woman of Year to be Named May 11; Tickets on Sale
1886 - Film director Robert N. Bradbury born in Washington state; launched John Wayne's career in Placerita Canyon [watch]
Homicide investigators from the Los Angeles County Sheriff's Department are dedicated to solving murders and putting suspects behind bars.
Canyon Country Man One of Two Arrested for 2017 Palmdale Stabbing Death
Asteady downpour and gray skies couldn't keep 44 chili chefs and a crowd of hungry guests away from Tuesday's Charity Chili Cook-off at Wolf Creek Brewery in Valencia.
Rainy-day Chili Warms the Heart for School Libraries
For 30 maybe 40 minutes after The Master's University returned to it locker room inside the bowels of Municipal Auditorium, Lawrence Russell sat at his locker.
NAIA Men’s Basketball All-Americans Include 3 Mustangs
The list of California State University, Northridge’s Distinguished Alumni Awards recipients is diverse and dynamic. In keeping with that theme, the university is adding three highly accomplished honorees from three different walks of life to the list in April.
CSUN Announces Recipients of Distinguished Alumni Awards
Enjoy a scenic ride through the Heritage Valley where the fragrance of orange and lemon blossoms are delightful, April 1, at 12:00 p.m on Fillmore & Western Railway's Easter Lunch Train.
April 1: Fillmore & Western Railway’s Easter Lunch Train
The Santa Clarita Arts Commission will hold a Study Session Monday, March 26, at 6:30 p.m.
March 26: Arts Commission Study Session
Barnes & Noble Valencia will be holding a Children's Story Time event, Saturday, March 31 from 1:00 p.m. - 3:00 p.m.
March 31: ‘Ernest Hummingbird’ Book Reading, Signing at Barnes & Noble
Adoption is a meaningful way for individuals and couples to fulfill their dream of parenting. There are approximately 64,000 children in foster care in California.
April 21: Foster/Foster-Adopt a Child Information Meeting
The County of Los Angeles Department of Animal Care and Control (DACC) continues to staff emergency shelters for animals and respond to requests for assistance due to the rainstorm event.
County Providing Emergency Animal Services During Storm
After a lengthy, valleywide search, the Newhall Family Theatre for the Performing Arts is proud to announce its inaugural Board of Directors.
Newhall Family Theatre Announces Inaugural Board of Directors
Acting on a motion by Supervisor Mark Ridley-Thomas, the Metropolitan Transportation Authority Board voted unanimously to consider building on the success of a pilot program that deployed two outreach teams along the Red Line to help homeless individuals aboard buses and trains, and in and around transit stations, obtain housing and other services.
Homeless Outreach Pilot Program Demonstrating its Worth
The Parkinson’s Foundation (PF) will host its annual Moving Day North LA, A Walk for Parkinson’s on April 28 during National Parkinson’s Disease (PD) Awareness Month.
April 28: Moving Day North LA Walk for Parkinson’s
There are still a few days left to purchase tickets and be eligible to win a brand new car, a 2018 Chevy Cruze, MSRP $22,385.
March 26: Deadline to Purchase WiSH Foundation’s Win a Car Tickets
Mandatory evacuations of the 8300 block to the 9000 block of La Tuna Canyon remain in effect. The following picture, taken one mile north of the 8300 block of La Tuna Canyon, is within the area that has been evacuated. No structures were damaged due to the erosion of this hillside.
Storm Causes Hillside Erosion in La Tuna Canyon Burn Area
When Master's coach Jason Semelsberger explained that his team finished in 11th place on Tuesday in large part because of a loaded field, it wasn't a throwaway line meant to make the Mustangs feel better or to pacify their fans. It was the truth.
Mustangs Hang Tough in Competitive Field
SACRAMENTO - Senator Scott Wilk, R-Antelope Valley on Wednesday introduced a senate resolution - Senate Resolution 96 - calling on the federal government to stop, once and for all, the proposed Cemex mega-mine near Santa Clarita and bring an end to a decades old battle between residents and the multinational conglomerate.
Wilk Bill Calls on Feds to End Cemex Mega-Mine
Chandra Subramaniam spent his first week as the new dean of California State University, Northridge’s David Nazarian College of Business and Economics in meeting after meeting, learning about the job and the people he’ll be working with.
CSUN Names New Dean of Nazarian Business College