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June 23
1946, 11:20pm: William S. Hart, 81, dies at L.A.'s California Lutheran Hospital, leaving his Newhall estate and his (now West) Hollywood home to the public [story]
Hart dies


The U.S. Food and Drug Administration today approved the Bio-Rad BioPlex 2200 HIV Ag-Ab assay, the first FDA-approved diagnostic that differentiates between HIV-1 antibodies, HIV-2 antibodies, and HIV-1 p24 antigen in human serum or plasma specimens.

Two major types of HIV have been identified: HIV-1 and HIV-2. HIV-1 is responsible for most HIV infections throughout the world. HIV-2 is found primarily in West Africa; however, cases of HIV-2 infection have been identified in the United States. HIV-1 and HIV-2 are similar, but distinct viruses.

hivstd3The Bio-Rad BioPlex 2200 HIV Ag-Ab assay is to aid in the diagnosis of infection with HIV-1 and/or HIV-2, including acute HIV-1 infection. It may be used in adults, children two years of age and older, as well as in pregnant women. The assay may also be used to screen organ donors for HIV-1/2 when the blood specimen is collected while the donor’s heart is still beating. However, the assay is not approved for use in screening blood or plasma donors, except in urgent situations where traditional licensed blood donor screening tests are unavailable or their use is impractical.

“Today’s approval provides healthcare professionals another option for the diagnosis of HIV infections,” said Karen Midthun, M.D., director of the FDA’s Center for Biologics Evaluation and Research. “The ability to diagnose HIV infection early and differentiate between types of infection is important in the care of individuals as both diseases exhibit the same symptoms but progress at different rates.”

HIV-2

HIV-2

HIV antigens and antibodies appear and are detectable at different stages of the infection. Early in the infection, HIV-1 antigen can be detected prior to the development of detectable levels of HIV-1 antibodies. Acute HIV-1 infection is identified when the blood specimen is positive for HIV-1 p24 antigen but is negative for HIV-1 and HIV-2 antibodies.

The Bio-Rad BioPlex 2200 HIV Ag-Ab assay allows results of antigen and antibody detection to be reported separately. In addition to distinguishing between established HIV-1 and HIV-2 infection, reporting of distinct results helps differentiate between acute and established HIV infection respectively.

The BioPlex 2200 HIV Ag-Ab assay is intended for use with the BioPlex 2200 System, which was cleared by the FDA in 2004. The new assay is manufactured by Bio-Rad Laboratories, Inc., based in Hercules, California.

fdaThe FDA, an agency within the U.S. Department of Health and Human Services, promotes and protects the public health by, among other things, assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation’s food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.

 

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LOCAL NEWS HEADLINES
Friday, Jun 20, 2025
June 28: Amateur Ham Radio National Field Day at Acton Park
Amateur Ham Radio National Field Day will be held Saturday, June 28, at Acton Park, noon to 9 p.m.
Thursday, Jun 19, 2025
Pioneer Oil Refinery Park Opens to the Public in Newhall
The Pioneer Oil Refinery off of Pine Street in Newhall was built in 1877 by California Star Oil works, forming the foundation for the West Coast oil industry. Benzene and kerosene were the main products made in the refinery and were later sold locally in Ventura and Santa Barbara.
Thursday, Jun 19, 2025
Santa Clarita Hiring for Positions at Hart Park
Love the outdoors? Passionate about community programs? The city of Santa Clarita is hiring part-time Recreation Leaders to help bring events, camps and nature programs to life at William S. Hart Park.
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Latest Additions to SCVNews.com
1946, 11:20pm: William S. Hart, 81, dies at L.A.'s California Lutheran Hospital, leaving his Newhall estate and his (now West) Hollywood home to the public [story]
Hart dies
1972 - Vasquez Rocks added to National Register of Historic Places [list]
Vasquez Rocks
The Agua Dulce Women's Club Community Blood Drive will be held Wednesday, June 25, 10 a.m.- 4 p.m. at 33201 Agua Dulce Canyon Road, Agua Dulce, CA 91390.
June 25: Agua Dulce Women’s Club Community Blood Drive
The regular meeting of the Saugus Union School District Governing Board of Trustees will be held Tuesday, June 24 beginning at 6:40 p.m. The board will first meet in closed session at 5:30 p.m.
June 24: Saugus Union School District Board Regular Meeting
1941 - Ernie Hickson buys out Trem Carr's interest in their Monogram movie ranch, renames it "Placeritos" (later called Melody) [story]
Ernie Hickson
The Santa Clarita Community College District Board of Trustees will hold a meeting Wednesday, June 25, beginning with a closed session at 2:30 p.m. The open session begins at 5 p.m.
June 25: COC Board to Conduct Self-Evaluation Retreat
The Santa Clarita Valley Food Pantry, the longest-running and largest food assistance organization in the SCV, has been selected by Albertsons Companies to receive a $30,000 makeover grant.
SCV Food Pantry to Receive $30K ‘Makeover’ from Albertsons
The Samuel Dixon Family Health Center invites the community to the Third Annual Cornhole Tournament on Saturday, June 21 at 11 a.m. at Lucky Luke Brewing Company.
June 21: Sam Dixon Cornhole Tournament at Lucky Luke Brewing
Calling all Los Angeles County artists and performers. If you're part of a dance, music, vocal, musical theater or circus group, you are encouraged to apply to be part of the 66th Annual L.A. County Holiday Celebration.
Performers Sought for Annual L.A. County Holiday Celebration
The Castaic Union School District Governing Board will hold its regular meeting Thursday, June 26 at 6 p.m. The board will first meet in closed session at 5 p.m.
June 26: CUSD Board of Trustees Regular Meeting
Amateur Ham Radio National Field Day will be held Saturday, June 28, at Acton Park, noon to 9 p.m.
June 28: Amateur Ham Radio National Field Day at Acton Park
For one weekend only, Matchbox Theatre Co. is bringing its inaugural production of Johnna Adams’ "World Builders" to The MAIN.
June 27-29: Matchbox Theatre to Present ‘World Builders’ at The MAIN
Vasquez Rocks Natural Area will host its "Pride Outside," event 4-7 p.m. Sunday, June 29.
June 29: Pride Outside at Vasquez Rocks
Caltrans has announced overnight lane reductions are scheduled on northbound and southbound Interstate 5 (I-5) south of Templin Highway starting Monday, June 23 for pavement rehabilitation.
June 23-27: Castaic Area I-5 Lane Closures
2002 - "Legacy: Santa Clarita's Living History" series debuts on SCVTV with "Placerita Gold" episode [watch]
Legacy
The Pioneer Oil Refinery off of Pine Street in Newhall was built in 1877 by California Star Oil works, forming the foundation for the West Coast oil industry. Benzene and kerosene were the main products made in the refinery and were later sold locally in Ventura and Santa Barbara.
Pioneer Oil Refinery Park Opens to the Public in Newhall
Old Town Newhall will host a "Sip into Summer" Bar Crawl, 8 p.m. Saturday, June 21 on Main Street.
June 21: Sip into Summer Bar Crawl On Main Street
I wanted to share a quick legislative update from Sacramento. We recently reached the deadline to send bills from the Senate to the Assembly in order to continue moving them through the legislative process this session.
Suzette Martinez Valladares | Report from the State Senate
The city of Santa Clarita is seeking Youth Basketball Coaches for the 2025 summer season.
Santa Clarita Volunteer Youth Basketball Coaches Needed
Love the outdoors? Passionate about community programs? The city of Santa Clarita is hiring part-time Recreation Leaders to help bring events, camps and nature programs to life at William S. Hart Park.
Santa Clarita Hiring for Positions at Hart Park
Harley-Davidson Santa Clarita will host a performance suspension workshop, 11 a.m.-3 p.m. Saturday, June 28 with a Q and A with experts from OHLINS Factory.
June 28: Harley-Davidson Santa Clarita Suspension Workshop
California Institute of the Arts was recently named in The Hollywood Reporter’s inaugural Top Animation Schools list for 2025.
CalArts Named One of ‘The Hollywood Reporter’s’ Top Animation Schools for 2025
ARTree Community Arts Center in collaboration with Santa Clarita Public Library are seeking teen volunteers to help create a bottle cap mural.
ARTree, Santa Clarita Library Seeks Volunteers for Bottle Cap Mural
SCVNews.com