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February 4
1822 - Surveyor Edward F. Beale born in Washington, D.C.; cut through Newhall Pass 40 years later, assembled 270,000-acre Tejon Ranch [story]
Edward Beale


| Wednesday, Jan 18, 2023
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3d illustration of a damaged and disintegrating cancer cell


By detecting cancer mutations, California State University, Northridge associate professor of biology Cristian Ruiz and his collaborators at Weill Cornell Medicine developed a new method for detecting cancer in its early stages.

If the assay is further successfully developed commercially, Ruiz said, doctors will be able to check individuals for early signs of cancer when they come in for routine check-ups, such as during annual physicals, using “liquid biopsies.”

Liquid biopsies are tests that use blood samples — such as those routinely used to check glucose and cholesterol levels — to detect cancer cells from a tumor, or their DNA, as opposed to directly sampling tumors in tissues, where it may be harder to obtain samples, or where it may be harder to find cancer cells because the tumor is at a very early stage. The aforementioned assay refers to an investigative procedure to determine the activity of a target, in this case, the target would be cancerous cells.

If researchers can detect cancers in their earliest stages using liquid biopsies, it would greatly improve the outcome for the patient’s health by allowing for interventions before cancers spread further or become harder to treat, Ruiz said.

“Having the ability to diagnose cancer at its earliest stages benefits the patient in a multitude of ways when regarding ovarian, colon, breast, and melanoma providing a prognosis improvement and a wider range of treatment options,” he explained.

In the fight against cancer, Ruiz said a powerful weapon would be the ability for adults approaching the age of 40 to make an appointment with their primary care physician, who, through a simple test — a liquid biopsy — could find out if something serious is developing inside their body.

The earlier the cancer cells are found, he said, medical professionals are better able to stop cancer’s spread throughout the entire body.

“A patient has a much greater chance of recovering from a minor operation to remove a tumor, or surviving in general, compared to treating metastatic cancers,” Ruiz said. “Early detection also means less time spent in the hospital, a fraction of the cost for treatments and an extended possibility for a healthy life.”

Ruiz’s specialty is molecular biology and microbiology. In addition to his cancer research, his main focus is studying antibiotic resistance. Research in his lab explores both the regulation, function and inhibition of bacterial multidrug efflux pumps, which play a major role in removal of antibiotics and other molecules. His lab also works on characterizing the genes of carbapenem-resistant superbugs, a type of bacteria that is extremely difficult to treat because of the way they resist antibiotics.

“For example, there were about 5 million deaths in 2019 associated with antibiotic resistant-bacteria; moreover, about 50 percent of people who have a blood infection with multi-drug resistant bacteria will die from the infection because of how little can be done in treatment,” Ruiz said. “This is why antibiotic resistance is our main focus. A better understanding of antibiotic resistance will contribute to developing better diagnostics tools and novel therapies to treat these life-threatening bacteria”.

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SCV NewsBreak
LOCAL NEWS HEADLINES
Friday, Feb 3, 2023
Friday COVID Roundup: L.A. County Remains in Low Community Level for Third Week
The Los Angeles County Department of Public Health confirmed 19 new deaths throughout L.A. County, 1,417 new cases countywide and 25 new cases in the Santa Clarita Valley.
Friday, Feb 3, 2023
Carousel Ranch ‘Carousel Wishes, Valentine Kisses’ Campaign
Carousel Ranch, a place where children with special needs discover and experience some of their greatest achievements through equestrian therapy and vocational training programs will celebrate its 26th anniversary this year.
Friday, Feb 3, 2023
Feb. 4: Additional Lane Closures Required Wiley Canyon/Orchard Village Roads
The city of Santa Clarita has announced that as part of the median modification work taking place at Orchard Village Road and Wiley Canyon Road, additional lane closures are required on Saturday, Feb. 4 for street grinding and paving.
Keep Up With Our Facebook

Latest Additions to SCVNews.com
1822 - Surveyor Edward F. Beale born in Washington, D.C.; cut through Newhall Pass 40 years later, assembled 270,000-acre Tejon Ranch [story]
Edward Beale
The Los Angeles County Department of Public Health confirmed 19 new deaths throughout L.A. County, 1,417 new cases countywide and 25 new cases in the Santa Clarita Valley.
Friday COVID Roundup: L.A. County Remains in Low Community Level for Third Week
Carousel Ranch, a place where children with special needs discover and experience some of their greatest achievements through equestrian therapy and vocational training programs will celebrate its 26th anniversary this year.
Carousel Ranch ‘Carousel Wishes, Valentine Kisses’ Campaign
One of my favorite aspects of the Fifth District is how many beautiful outdoor areas we have to enjoy.
Kathryn Barger | Keeping up with Kathryn
The city of Santa Clarita has announced that as part of the median modification work taking place at Orchard Village Road and Wiley Canyon Road, additional lane closures are required on Saturday, Feb. 4 for street grinding and paving.
Feb. 4: Additional Lane Closures Required Wiley Canyon/Orchard Village Roads
The California Public Utilities Commission has voted to accelerate the timeframe in which residential energy customers will receive a Climate Credit on their bills in order to provide much needed support to customers experiencing unusually high natural gas bills this winter.
SCV Utility Customers to Receive Accelerated Climate Credit
The Relay For Life of Santa Clarita Valley benefiting the American Cancer Society invites you to join their Spring “YUMraising” event with See’s Candy.
Relay for Life SCV See’s Candy Fundraiser Benefits American Cancer Society
"Mind Over Marijuana" is the California Department of Public Health’s new educational campaign to inform youth about the dangers of underage cannabis use, and how it can impact their social and emotional wellbeing later in life.
CDPH Launches Youth Cannabis Prevention Initiative
The Santa Clarita Valley Water Agency was recently awarded a $5 million grant under the United States Bureau of Reclamation’s WaterSmart Drought Response Program funded through President Joe Biden’s Bipartisan Infrastructure Law.
SCV Water Awarded $5 Million for Regional Drought Resiliency Project
For the fourth consecutive year, Providence Holy Cross Medical Center has been named among America’s 50 Best Hospitals, which recognizes excellence and outstanding patient outcomes.
Holy Cross Among America’s 50 Best Hospitals
The Santa Clarita Artists Association has issued a "call to artists" to participate in its "Colors of the Rainbow" gallery show which will be held March 3 to April 8.
Feb. 16: Entry Deadline SCAA Gallery Show ‘Colors of the Rainbow’
1998 - As disbelief about El Niño was starting to set in, the first of a month-long succession of devastating storms hits [story]
winter storm
The Master's men's and women's track & field teams traveled to Claremont, Calif. Saturday for the CMS Outdoor Indoor Distances Meet and came away with school records, personal bests and national championship qualifications.
Mustangs Open Track & Field Season on High Note
College of the Canyons won its second straight conference contest 64-55 over visiting Bakersfield College on Wednesday, as Jonah El-Farra and Andrew Henderson combined to put the Cougars over the top.
Cougs Win Second Straight Game with Victory Over Bakersfield 64-55
As schools throughout California struggle to secure funding to keep music and arts education afloat, Oksana Kolesnikova, an immigrant and internationally acclaimed pianist, is making sure students throughout Los Angeles County, including Santa Clarita, can experience the proven benefits that music and other extracurricular activities have to offer.
Acclaimed Pianist Offering Local After-School Enrichment Programs
SCV Water, in partnership with the Association of California Water Agencies, is pleased to introduce the Edward G. “Jerry” Gladbach Scholarship.
SCV Water, ACWA Partner to Establish Jerry Gladbach Scholarship
Kevin A. Klockenga has been appointed president and chief executive officer of Henry Mayo Newhall Hospital.
Henry Mayo Names Kevin Klockenga New President, CEO
The city of Santa Clarita, in partnership with Santa Clarita Sister Cities, invites local students to submit original artwork, poetry, essays/creative writing, photographs or music for the 2023 Young Artists and Authors Showcase.
City Accepting Entries for Sister Cities Young Artists, Authors Showcase
The Santa Clarita Valley Water Agency’s Water Resources and Watershed Committee is holding an in-person meeting Wednesday, Feb. 8, at 5:30 p.m.
Feb. 8: SCV Water Resources, Watershed Committee Meeting
Producer Fred Blanco brings "The Great Wildcat Jackson" to The MAIN Friday, Feb. 17-Sunday, Feb. 19
‘The Great Wildcat Jackson’ Coming to The MAIN
Child & Family Center presents its 34th annual Taste of the Town on Sunday, May 7.
Taste of the Town Tickets Benefiting Child & Family Center On Sale Now
State Sen. Scott Wilk, R-Santa Clarita, announced Thursday he has been asked to serve as vice chair of the Senate Judiciary Committee.
Wilk to Serve as Vice Chair of Senate Judiciary Committee
As we step into the month of love, let's take a moment to reflect on the progress we made in January!
Message from JCI Santa Clarita President Cindy Curtis
The month of February is probably best known for the holiday of love, which falls on Feb. 14.
Monthly Message from City Manager | Say ‘I Do’ at City Hall – February 2023
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